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Mitochondrial Open Reading Frame of the 12S rRNA-c · Lyophilized Powder
MOTS-c is a mitochondria-derived peptide (MDP) encoded within the 12S rRNA gene of mitochondrial DNA. It is studied for its role in mitochondrial biogenesis, metabolic regulation, and AMPK pathway activation in research models.
For Research Use Only · Not for Human Consumption
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide that is uniquely derived from mitochondrial DNA. It represents a new class of mitochondria-derived peptides (MDPs) that has garnered interest for its ability to influence metabolic function through AMPK and related pathways.
Supplied as lyophilized powder at ≥99% purity by HPLC. Full batch COA included with every order.
MOTS-c is one of the first peptides discovered to be encoded by mitochondrial DNA rather than nuclear DNA. This unique origin makes it a highly relevant compound for researchers exploring mitochondria–nucleus communication, metabolic diseases, and cellular energy regulation.
For research use only. Consult relevant protocols before use.
Certificate of Analysis
Mitochondrial-Derived Peptide
Amino Acid Sequence
Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
16-mer mitochondria-derived peptide encoded by 12S rRNA small open reading frame (sORF)
| Test Parameter | Specification | Result |
|---|---|---|
| Appearance | Conforms to specification: White lyophilized powder | PASS — White lyophilized powder |
| Purity / Assay | ≥99.0% (HPLC) | PASS — 99.1% |
| Identity | Conforms to reference standard (MS / HPLC) | PASS — Confirmed |
| Solubility | Soluble per specification | PASS — Clear solution |
